FAA-H-8083-25C · Source PDF page 426
Aeromedical Factors
Histotoxic Hypoxia · PHAK page 17-4
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need it. An arm or leg “going to sleep” because the blood endurance or acclimatization. When flying at high altitudes,
flow has accidentally been shut off is one form of stagnant it is paramount that oxygen be used to avoid the effects of
hypoxia. This kind of hypoxia can also result from shock, hypoxia. The term “time of useful consciousness” describes
the heart failing to pump blood effectively, or a constricted the maximum time the pilot has to make rational, life-saving
artery. During flight, stagnant hypoxia can occur with decisions and carry them out at a given altitude without
excessive acceleration of gravity (Gs). Cold temperatures supplemental oxygen. As altitude increases above 10,000
can also reduce circulation and decrease the blood supplied feet, the symptoms of hypoxia increase in severity, and the
to extremities. time of useful consciousness rapidly decreases. [Figure 17-1]
Since symptoms of hypoxia can be different for each
Histotoxic Hypoxia individual, the ability to recognize hypoxia can be greatly
The inability of the cells to effectively use oxygen is defined improved by experiencing and witnessing the effects of it
as histotoxic hypoxia. “Histo” refers to tissues or cells, and during an altitude chamber “flight.” The Federal Aviation
“toxic” means poisonous. In this case, enough oxygen is being Administration (FAA) provides this opportunity through
transported to the cells that need it, but they are unable to make aviation physiology training, which is conducted at the FAA
use of it. This impairment of cellular respiration can be caused CAMI in Oklahoma City, Oklahoma, and at many military
by alcohol and other drugs, such as narcotics and poisons. facilities across the United States. For information about the
Research has shown that drinking one ounce of alcohol can FAA’s one-day physiological training course with altitude
equate to an additional 2,000 feet of physiological altitude. chamber and vertigo demonstrations, visit the FAA website
at www.faa.gov.
Symptoms of Hypoxia
High-altitude flying can place a pilot in danger of becoming Hyperventilation
hypoxic. Oxygen starvation causes the brain and other vital Hyperventilation is the excessive rate and depth of respiration
organs to become impaired. The first symptoms of hypoxia leading to abnormal loss of carbon dioxide from the blood.
can include euphoria and a carefree feeling. With increased This condition occurs more often among pilots than is
oxygen starvation, the extremities become less responsive and generally recognized. It seldom incapacitates completely, but
flying becomes less coordinated. The symptoms of hypoxia it causes disturbing symptoms that can alarm the uninformed
vary with the individual, but common symptoms include: pilot. In such cases, increased breathing rate and anxiety
further aggravate the problem. Hyperventilation can lead to
• Cyanosis (blue fingernails and lips)
unconsciousness due to the respiratory system’s overriding
• Headache mechanism to regain control of breathing.
• Decreased response to stimuli and increased reaction
Pilots encountering an unexpected stressful situation may
time
subconsciously increase their breathing rate. If flying at
• Impaired judgment
higher altitudes, either with or without oxygen, a pilot may
• Euphoria have a tendency to breathe more rapidly than normal, which
often leads to hyperventilation.
• Visual impairment
• Drowsiness
Since many of the symptoms of hyperventilation are similar
• Lightheaded or dizzy sensation to those of hypoxia, it is important to correctly diagnose and
treat the proper condition. If using supplemental oxygen,
• Tingling in fingers and toes
check the equipment and flow rate to ensure the symptoms are
• Numbness
Altitude Time of useful consciousness
As hypoxia worsens, the field of vision begins to narrow and
instrument interpretation can become difficult. Even with all 45,000 feet MSL 9 to 15 seconds
these symptoms, the effects of hypoxia can cause a pilot to 40,000 feet MSL 15 to 20 seconds
have a false sense of security and be deceived into believing 35,000 feet MSL 30 to 60 seconds
everything is normal. 30,000 feet MSL 1 to 2 minutes
28,000 feet MSL 2½ to 3 minutes
Treatment of Hypoxia 25,000 feet MSL 3 to 5 minutes
Treatment for hypoxia includes flying at lower altitudes and/ 22,000 feet MSL 5 to 10 minutes
or using supplemental oxygen. All pilots are susceptible 20,000 feet MSL 30 minutes or more
to the effects of oxygen starvation, regardless of physical
Figure 17-1. Time of useful consciousness.
17-4